Chronic myelogenous leukemia in children

A case of chronic myelogenous leukemia in a 4 month old Filipino infant, whose apparent onset was at 2 months of age, is reported. The clinical course and hematological picture of this case followed the usual features of the disease as observed in infants mainly that of hepatosplenomegaly with bleeding manifestations, hyperleukocytosis with anemia and thrombocytopenia, and a relatively short course unresponsive with the usual therapeutic measures for chronic myelogenous leukemia. Terminally the patient manifested the picture of "blastic" crisis. (Summary)